Endocrine Abstracts

Thyroid cancer is the most common endocrine malignancy. It is known that cancer progression involve dysregulation of growth factors (FGFs) and their receptors (FGFRs) have been identified. In thyroid tumors. In particular, FGFR1 and FGFR3 are expressed in most well differenziated tumors, FGFR4 is predominantly expressed in aggressive tumor types and cells lines, while FGFR2 is the only receptor consistently detected in normal human thyroid tissue and its expression is downmodu...